The Island's Paul McBride will play in both sessions on day one as Great Britain and Ireland attempts to win the Walker Cup on US soil for only the third time.
The 21-year old partners Scotland's Connor Syme at number two in the foursomes against US Amateur champion Doc Redman and his Wake Forest team mate Will Zalatoris.
England's Matthew Jordan and Scotland's Robert MacIntyre will debut in the singles.
Alfie Plant, who leads off the foursomes with Harry Ellis against Collin Morikawa and Norman Xiong, is rested in the afternoon.
Scott Gregory and Jack Singh Brar go at No 3 against Scottie Scheffler and Cameron Champ with Welsh pair David Boote and Jack Davidson facing Maverick McNealy and Doug Ghim.
McBride faces Morikawa, 20, in the singles.
The Californian won the 2017 Northeast Amateur and was the Sunnehanna Amateur runner-up, losing to Braden Thornberry in a three-hole playoff. He also tied for second in the Trans-Mississippi Amateur.
46th Walker Cup Match - Saturday's Pairings and Tee Times, The Los Angeles Country Club (North Course, 7,397 yards, par 70)
All Times Irish time
Great Britain and Ireland vs. United States
- 1515 – Harry Ellis and Alfie Plant, GB&I vs. Collin Morikawa and Norman Xiong, USA
- 1530 – Connor Syme and Paul McBride, GB&I vs. Doc Redman and Will Zalatoris, USA
- 1545 – Scott Gregory and Jack Singh Brar, GB&I vs. Scottie Scheffler and Cameron Champ, USA
- 1600 – David Boote and Jack Davidson, GB&I vs. Maverick McNealy and Doug Ghim, USA
- 2045 – Harry Ellis, GB&I vs. Braden Thornberry, USA
- 2055 – Connor Syme, GB&I vs. Norman Xiong, USA
- 2105 – Jack Singh Brar, GB&I vs. Stewart Hagestad, USA
- 2115 – Paul McBride, GB&I vs. Collin Morikawa, USA
- 2125 – Matthew Jordan, GB&I vs. Will Zalatoris, USA
- 2135 – Robert MacIntyre, GB&I vs. Cameron Champ, USA
- 2145 – David Boote, GB&I vs. Doug Ghim, USA
- 2155 – Scott Gregory, GB&I vs. Maverick McNealy, USA